This problem will only occur under Vista.
1) Right click on the Microstudio Icon, Left click Properties
2) Left click the Compatibility Tab
3) Uncheck where it states “Run this Program in Compatibility Mode for:” if this is checked.
4) Make sure that there is a CHECK beside, “Run this program as an Administrator” under Privilege Level at the bottom of the Compatibility Tab.
5) Click Apply and Ok to close this.
6) Now Try Microstudio Again and let me know what happens.